San Luis, Arizona: A Gateway for Economic Growth. Nestled on the U.S. - Mexico border alongside its sister city, San Luis Río Colorado, San Luis, Arizona, is a thriving hub of opportunity. With a strong economic base in professional services, retail, agribusiness, and light industry, San Luis continues to grow while maintaining its welcoming, family-oriented atmosphere and low cost of living. The city boasts affordable housing, excellent educational opportunities, and vibrant recreational spaces, making it a great place to live and work. San Luis is also a key player in international trade, with two state-of-the-art Ports of Entry facilitating efficient commercial and pedestrian traffic. The city’s industrial expansion includes new parks and facilities linked to the Area Service Highway, enabling seamless access to Interstate 8. As a center for agriculture and a growing industrial hub, San Luis is poised for continued economic success, providing businesses with the infrastructure and community support needed to thrive.